A PHYLOGENETIC SURVEY OF MYOTUBULARIN GENES OF EUKARYOTES: DISTRIBUTION, PROTEIN STRUCTURE, EVOLUTION, AND GENE EXPRESSION

A phylogenetic survey of myotubularin genes of eukaryotes: distribution, protein structure, evolution, and gene expression

Abstract Background Phosphorylated phosphatidylinositol (PtdIns) lipids, produced and modified by PtdIns kinases and phosphatases, are critical to the regulation of diverse cellular functions.The myotubularin PtdIns-phosphate phosphatases have been well characterized in yeast and especially animals, where multiple isoforms, both catalytically activ

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Case report: Psychosis and catatonia in an adolescent patient with adipsic hypernatremia and autoantibodies against the subfornical organ

This is the first description of a patient in which adipsic hypernatremia, a rare autoimmune encephalitis, presented in combination with complex psychiatric symptomatology, including psychosis and catatonia.Adipsic hypernatremia is characterized by autoantibodies against the thirst center of the brain.These autoantibodies cause inflammation and apo

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